Literature summary extracted from

He, X.; Li, S.; Kaminskyj, S.G.W.
Overexpression of Aspergillus nidulans alpha-1,3-glucan synthase increases cellular adhesion and causes cell wall defects (2018), Med. Mycol., 56, 645-648 .

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
2.4.1.183	gene agsB, quantitative PCR enzyme expression analysis, constitutive overexpression in Aspergillus nidulans. The high level of agsB expression is deleterious	Aspergillus nidulans

Protein Variants

EC Number	Protein Variants	Comment	Organism
2.4.1.183	additional information	generation of an Aspergillus nidulans alpha-1,3-glucan in constitutive overexpression strain. Constitutive high-level alpha-1,3-glucan synthase activity increases hyphal wall thickness, but colonies grow slowly and sporulate poorly and have much higher adhesion to hydrophobic materials. In contrast to the wild-type strain, the overexpression strain forms a biofilm-like structure in plastic culture wells that is as adhesive as wild-type Aspergillus fumigatus. The high level of agsB expression is deleterious. Phenotype, overview	Aspergillus nidulans

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
2.4.1.183	cell wall	-	Aspergillus nidulans	5618	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.4.1.183	Aspergillus nidulans	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.4.1.183	mycelium	-	Aspergillus nidulans	-

Synonyms

EC Number	Synonyms	Comment	Organism
2.4.1.183	agsB	-	Aspergillus nidulans

General Information

EC Number	General Information	Comment	Organism
2.4.1.183	malfunction	overexpression of Aspergillus nidulans alpha-1,3-glucan synthase increases cellular adhesion and causes cell wall defects	Aspergillus nidulans
2.4.1.183	physiological function	alpha-1,3-glucan has important roles in fungal cellular adhesion and may contribute to fungal pathogenesis	Aspergillus nidulans

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Release 2023.1 (January 2023)